If you lose signal you can't directly control the drone. Just a very quick search produced these:
Article 8 of the The Chicago Convention (which many countries have signed up to and is referenced in the UK drone regulations) requires that “each contracting State undertake to insure that the flight of such aircraft without a pilot in regions open to civil aircraft shall be so controlled as to obviate danger to civil aircraft”.
CAP 722 in the UK says "suitable radio equipment must be fitted in order to be able to effect positive control over the UA at all times."
EASA regulations say that "autonomous drones need a level of verification of compliance with the technical requirements that is not compatible with the system put in place for the ’open’ category. Autonomous operations are, instead, allowed in the ’specific’ category, where the Regulation includes a tool flexible enough to verify requirements with the appropriate level of robustness". EASA defines autonomous drones as "An autonomous drone is able to conduct a safe flight without the intervention of a pilot. It does so with the help of artificial intelligence, enabling it to cope with all kinds of unforeseen and unpredictable emergency situations".