Can you fly normally all the time with the prop guards?
Yes.
I've flown in Sport mode and zig-zaged around with no problems.
I leave them on my Spark as my case accommodates the fit but with the MA2 I have to install before flight.
I think the best thing I like about them is that I can carry my aircraft with my pinky finger if I don't want to bring the case with me when walking on a trail.